Recombinant human Interferon-α2b
| Product ID |
hRP-A0813-EC |
| Lot# |
20060101 |
| Protein Accession |
NP_000596 |
| Symbol |
IFN-α2b |
| Description |
Recombinant human Interferon-α2b |
| Summary |
Interferon belongs to the cytokines family of proteins which are produced by mammalian cells in response to foreign agents such as viruses and tumor cells. It stimulates the production of two enzymes protein kinase and an oligoadenylate synthetase.
Interferon alpha is a type 1 class of interferon produced by human leukocytes and has antiviral properties. Interferon alpha 2b is a recombinant protein produced in E. coli with a molecular mass of 19269 Dalton. It is a single, non-glycosylated, polypeptide chain containing 165 amino acids. The Interferon-alpha 2b gene was derived from human leukocytes. INF alpha 2b protein was purified using affinity chromatography |
| Source |
E. coli |
| Isoelectric focusing |
5.8~6.3 |
| MW |
19269 Dalton |
| Bioactivity |
> 2.0X 108 I.U. ~ 2.21× 108 I.U. /ml |
| Potency |
> 1.4× 108 ~ 1.87× 108 I.U./mg protein |
| Bacterial endotoxins |
< 100 E.U. of endotoxin in the volume that contains 1.0 mg of protein. |
| Formulation and Storage |
Lyophilized colorless power. Can be reconstituted in phosphate buffered saline (PBS) containing 0.1% bovine serum albumin (BSA). Store at -80oC, avoid repeated freeze-thaw cycles. |
| Size |
100, 1000μg |
| Purity |
> 95%, as determined by SDS-PAGE and HPLC. |
| Application |
ELISA, Western Blot, Antibody Production, Arrays |
| |
| General protein Annotation Information |
| Entrez Gene ID |
3440 |
| Accessoion # |
Primary:NM_000605 |
| Other related: AC_000052,
AL353732,
AY255838,
AY532915,
BC074936,
BC074937,
BC104163,
BC104164,
CH471071,
CR541921,
J00207,
M28028,
M29883,
M54886,
NC_000009,
NT_008413,
NW_924062,
S64979,
S64991,
S64994,
V00544,
V00548,
V00549,
Y11834, |
| Synonyms |
IFNA, INFA2, MGC125764, MGC125765; Leukocyte interferon, B cell interferon, Type I interferon, IFNA2, IFN-α 2a, Interferon alpha-A, LeIF A, Interferon alpha-2; Interferon alpha-2 Precursor |
| SwissProt |
P01563 |
| OMIM |
147562 |
| PubMed |
10339405, 10477584, 11888273, 12010658, 12089333, 12477932, 1381203, 1385305, 15004750, 15233997, 15481145, 16160188, 16171819, 16278001, 16418394, 16697656, 16920161, 17116765, 17180012, 17181634, 17477817, 17880940, 18005734, 1834641, 1905933, 2049076, 2552026, 3906813, 6158094, 6159537, 6159538, 6162107, 6163083, 6164056, 6170983, 6310510, 7511078, 7526537, 7583919, 7627809, 7815507, 7904170, 7913356, 8234245, 8345204, 8366289, 8438572, 8661419, 8668211, 8764000, 8994971, 9108403, 9225992, 9343822, 9417943, 9425112, 9658081, 9694076, 9865497 |
| |
| Sequence Information |
| Nucleotide Length |
567 (see ORF) |
| Peptide Length |
188 (see peptide) |
|
